Peyronie’s Disease is a disease that has no known origin. It is identified by a plaque or hard lump that develops in the penis. The plaque forms on the upper or lower part of the penis, with erectile tissue in layers. It appears with a localized inflammation and can progress to the formation of a hardened scar.

Francois de la Peyronie, a French surgeon, first described Peyronie’s Disease in 1743. The first writers to describe it were an impotence type, now referred to as Erectile dysfunction. Peyronie’s Disease can be linked with ED, but experts today recognize ED as a single factor that causes the condition, which isn’t always evident.

The symptoms of Peyronie’s Disease vary from mild to very severe. It can be a slow-onset disease or suddenly, sometimes in the night. In the most severe instances, the hardened plaque decreases flexibility, which can cause discomfort and cause your penis to bend or arch in the erection. In most cases, the pain diminishes with time; however, the penis’s bend could remain an issue and make sexual intimacy difficult. In the milder version of the Disease, the inflammation could heal without causing severe discomfort or permanent bending. The plaque itself isn’t cancerous. Plaque on one of the sides of the shaft (most often) will cause the penis to flex upwards. A plaque on the underside causes it to flex downward. Sometimes, the plaque grows on both the top and bottom, which causes indentation and shortening of the penis. Sometimes the pain, bending and emotional stress can hinder sexual relations.

A study has found that Peyronie’s Disease occurs in 1% of males. Although the condition is prevalent in middle age, younger and older men are also susceptible to developing it. Genetic factors may cause a person to be susceptible to the Disease. Men who suffer from the Disease seek medical attention due to discomfort in their erections and difficulties in having intercourse. Because the causes of the condition and its progress aren’t well-understood medical professionals treat the condition by using a method of observation, which means they prescribe and maintain techniques that seem to work.

The aim of treatment can be to keep the patients sexually engaged. Giving them information on the condition and its treatment is usually all that is needed. No solid evidence suggests that any treatment other than surgery is more effective. Most experts recommend surgery when the patient is in a long-term situation where the condition is stable and the deformity does not prevent intercourse.

The course of the Disease

Many scientists believe that Peyronie’s disease plaque is formed following trauma (hitting or breaking) which causes localized bleeding within the penis. Two chambers, known as the corpora cavernosa, run across the penis. The membrane that covers the inner surface of the chambers is a layer consisting of elastic fibres. A connective tissue, the septum, runs through the middle of each chamber and connects to the bottom and top. When the penis has been bent or bumped, the region where the septum connects with the elastic fibres could extend beyond the limit and result in injury to the interior of the erectile compartment and, for example, the rupture of smaller blood vessels. Because of age, a decrease in elasticity around the attachment point of the septum could increase the chance of damage. The affected area could be healed slowly or in a different way for two reasons: repeated traumas and an insufficient amount of blood flow within hearths-like fibres. When the area heals in around a year, plaque cannot progress beyond the initial inflammation phase.

Suppose the condition persists for a long time. In that case, the plaque will undergo the process of fibrosis, which is the formation of fibrous and tough tissue and even calcification, which is the formation of calcium-rich deposits. Although trauma could cause the sudden onset of cases of Peyronie’s Disease, it’s not the only reason why most cases develop slowly and without obvious trauma. This is also not a reason why some cases can disappear in a hurry. Researchers have speculated that Peyronie’s Disease could be an autoimmune condition.


The course of the Disease varies for every patient. Patients who experience improvement do not require treatment. Experts in medicine recommend that patients wait for one to two years or more before attempting to correct the issue surgically. While waiting, patients may be ready to undergo procedures without established efficacy. Researchers have given vitamin E to people suffering from the disease in small-scale studies, and have reported improvements. However, no controlled studies have confirmed the efficacy of vitamin E treatment. Steroids like cortisone have caused undesirable adverse effects, like the death or atrophy of healthy tissues.

Radiation therapy, where high-energy radiation is directed at the plaque, is employed. As with other treatment options, the chemical is believed to ease pain; however, it does not impact the actual plaque. It also may cause unwanted adverse negative effects. While the diversity of the agents and techniques used to point towards the absence of a clinically proven treatment, the latest research on the healing process could one day lead to more effective treatments.

The condition has been successfully treated with surgical techniques, but only with a limited degree of results. The two most commonly used surgical options are expanding or removing the plaque, then placing an area of skin or synthetic material, and removing or pinching tissues from the penis side that is opposite to the plaque, which eliminates the bending effect. The first procedure can result in the loss of some erectile function, particularly rigidity. The second technique, also known as the Nesbit procedure, is a method of erectile dysfunction that involves reducing the Nesbit procedure, resulting in an erect penis.

Certain men opt to get implanted devices that increase the stiffness of their penis. In some instances, the implant will satisfactorily straighten the penis. In other instances, implantation is combined with the technique of making incisions and grafting (pinching and folding skin) if the implant itself doesn’t make the penis straighter.

peyronie’s surgery Brampton Many types of surgery yield positive outcomes. However, because complications may occur, and as a lot of the conditions that are associated with the condition (for instance, a shortening of the penis) cannot be corrected through surgical procedures, doctors tend to only perform surgery on the few patients with a curvature that is severe enough to prevent sexual contact.

See a qualified doctor if you suspect you are suffering from penile enlargement Brampton.

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